摘要: The discovery that certain high-risk strains of human papillomavirus (HR-HPV) cause nearly 100% invasive cervical cancer has spurred a revolution in prevention by promoting the development viral vaccines. Although efficacy these vaccines already been demonstrated, complete understanding latency and natural immunity is lacking, solving mysteries could help guide policies screening vaccine use. Here, we examine epidemiological biological history HPV infection, with an eye toward using studies to implementation strategies.
elsevier.com
dm5migu4zj3pb.cloudfront.net 
researchgate.net 参考文章(77)
Andrew Lackner, Ronald Veazey, The mucosal immune system and HIV-1 infection. Aids Reviews. ,vol. 5, pp. 245- 252 ,(2003)
M. J. Shikowitz, C. A. Amella, M. Nouri, B. M. Steinberg, L. A. Lofgren, A. M. Ronn, Latent infection induced with cottontail rabbit papillomavirus. A model for human papillomavirus latency. American Journal of Pathology. ,vol. 144, pp. 1167- 1171 ,(1994)
Vanessa Schick, Debby Herbenick, Michael Reece, Stephanie A. Sanders, Brian Dodge, Susan E. Middlestadt, J. Dennis Fortenberry, Sexual Behaviors, Condom Use, and Sexual Health of Americans Over 50: Implications for Sexual Health Promotion for Older Adults The Journal of Sexual Medicine. ,vol. 7, pp. 315- 329 ,(2010) , 10.1111/J.1743-6109.2010.02013.X
A. Maran, C.A. Amella, T.P. Di Lorenzo, K.J. Auborn, L.B. Taichman, B.M. Steinberg, Human Papillomavirus Type 11 Transcripts Are Present at Low Abundance in Latently Infected Respiratory Tissues Virology. ,vol. 212, pp. 285- 294 ,(1995) , 10.1006/VIRO.1995.1486
Martyn Plummer, Rolando Herrero, Silvia Franceschi, Chris J.L.M. Meijer, Peter Snijders, F. Xavier Bosch, Silvia de Sanjosé, Nubia Muñoz, Smoking and cervical cancer: pooled analysis of the IARC multi-centric case–control study Cancer Causes & Control. ,vol. 14, pp. 805- 814 ,(2003) , 10.1023/B:CACO.0000003811.98261.3E
Stuart Collins, Terry P. Rollason, Lawrence S. Young, Ciaran B.J. Woodman, Cigarette smoking is an independent risk factor for cervical intraepithelial neoplasia in young women : a longitudinal study European Journal of Cancer. ,vol. 46, pp. 405- 411 ,(2010) , 10.1016/J.EJCA.2009.09.015
Joseph J. Mattapallil, Daniel C. Douek, Brenna Hill, Yoshiaki Nishimura, Malcolm Martin, Mario Roederer, Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection Nature. ,vol. 434, pp. 1093- 1097 ,(2005) , 10.1038/NATURE03501
F. Xavier Bosch, Ann N. Burchell, Mark Schiffman, Anna R. Giuliano, Silvia de Sanjose, Laia Bruni, Guillermo Tortolero-Luna, Susanne Kruger Kjaer, Nubia Muñoz, Epidemiology and natural history of human papillomavirus infections and type-specific implications in cervical neoplasia. Vaccine. ,vol. 26, ,(2008) , 10.1016/J.VACCINE.2008.05.064
Jan M. M. Walboomers, Marcel V. Jacobs, M. Michele Manos, F. Xavier Bosch, J. Alain Kummer, Keerti V. Shah, Peter J. F. Snijders, Julian Peto, Chris J. L. M. Meijer, Nubia Mu�oz, Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. The Journal of Pathology. ,vol. 189, pp. 12- 19 ,(1999) , 10.1002/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F