Detection of oncogenic genital human papillomavirus (HPV) among HPV negative older and younger women after 7 years of follow-up.

摘要: The knowledge on risk factors of being human papillomavirus (HPV)-positive among older women is sparse. aim was to determine the frequency oncogenic HPV appearance after 7 years initially HPV-negative and examine potential that influence occurrence in using multiple logistic regression. For comparison, a younger cohort examined under identical study settings included. This prospective comprised 1,577 (age 40–50 at enrolment) 2,920 aged 22–32. Participants were interviewed underwent gynecological examination two time points (7 apart). Cervical samples tested for Hybrid Capture 2 (HC2) only who HC2-negative baseline prevalence 6.4% 10.7%, respectively, there no “second peak” observed women. Recent sexual partners strong determinant irrespective age. Lifetime number significant factor women, even adjustment recent behavior. In addition, menopause associated with non-significantly increased follow-up. conclusion, previously may be due both behavior previous exposure is, reactivation latent infection. J. Med. Virol. 86:975–982, 2014. © 2014 Wiley Periodicals, Inc.