MiR-145 inhibits tumor angiogenesis and growth by N-RAS and VEGF

作者: Chao Zou , Qing Xu , Feng Mao , Dan Li , Chuanxiu Bian

DOI: 10.4161/CC.20598

关键词:

摘要: … effects of miR-145 on inhibiting angiogenesis and invasion in vitro. (A) tube formation assay of HUVeC. A significant decrease was observed in the cells transfected with miR-145 …

参考文章(42)
Karl Simin, Hua Wu, Lucy Lu, Dan Pinkel, Donna Albertson, Robert D Cardiff, Terry Van Dyke, pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia PLOS Biology. ,vol. 2, ,(2004) , 10.1371/JOURNAL.PBIO.0020022
Sonia Mohinta, Hailong Wu, Priyasri Chaurasia, Kounosuke Watabe, Wnt pathway and breast cancer Frontiers in Bioscience. ,vol. 12, pp. 4020- ,(2007) , 10.2741/2368
Gaspare La Rocca, Bin Shi, Margherita Badin, Tiziana De Angelis, Laura Sepp-Lorenzino, Renato Baserga, Growth inhibition by microRNAs that target the insulin receptor substrate-1 Cell Cycle. ,vol. 8, pp. 2255- 2259 ,(2009) , 10.4161/CC.8.14.9026
Masayuki Kano, Naohiko Seki, Naoko Kikkawa, Lisa Fujimura, Isamu Hoshino, Yasunori Akutsu, Takeshi Chiyomaru, Hideki Enokida, Masayuki Nakagawa, Hisahiro Matsubara, miR‐145, miR‐133a and miR‐133b: Tumor‐suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma International Journal of Cancer. ,vol. 127, pp. 2804- 2814 ,(2010) , 10.1002/IJC.25284
Mark Stearns, Jordan Tran, Mary Kay Francis, Hong Zhang, Christian Sell, Activated Ras Enhances Insulin-Like Growth Factor I Induction of Vascular Endothelial Growth Factor in Prostate Epithelial Cells Cancer Research. ,vol. 65, pp. 2085- 2088 ,(2005) , 10.1158/0008-5472.CAN-04-4100
M Götte, C Mohr, C-Y Koo, C Stock, A-K Vaske, M Viola, S A Ibrahim, S Peddibhotla, Y H-F Teng, J-Y Low, K Ebnet, L Kiesel, G W Yip, miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness. Oncogene. ,vol. 29, pp. 6569- 6580 ,(2010) , 10.1038/ONC.2010.386
Changju Qu, Zhihui Liang, JiaLing Huang, Ruiying Zhao, Chunhui Su, Sumei Wang, Xudan Wang, Rong Zhang, Mong-Hong Lee, Huiling Yang, MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN Cell Cycle. ,vol. 11, pp. 785- 796 ,(2012) , 10.4161/CC.11.4.19228
Alex Gregorieff, Hans Clevers, Wnt signaling in the intestinal epithelium: from endoderm to cancer Genes & Development. ,vol. 19, pp. 877- 890 ,(2005) , 10.1101/GAD.1295405
M. Yamakuchi, C. D. Lotterman, C. Bao, R. H. Hruban, B. Karim, J. T. Mendell, D. Huso, C. J. Lowenstein, P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 6334- 6339 ,(2010) , 10.1073/PNAS.0911082107
Axel Grothey, Evanthia Galanis, Targeting angiogenesis: progress with anti-VEGF treatment with large molecules. Nature Reviews Clinical Oncology. ,vol. 6, pp. 507- 518 ,(2009) , 10.1038/NRCLINONC.2009.110