Passive cutaneous anaphylaxis with antibody fragments.
作者： Z. Ovary , A. Taranta
DOI: 10.1126/SCIENCE.140.3563.193
关键词:
摘要: Pepsin-digested rabbit antibody (5S) provoked reverse passive cutaneous anaphylaxis in the guinea pig, but was somewhat less effective, mole for mole, than native antibody. Fixation of pig complement by pepsin-digested could not be demonstrated either vitro or vivo. Splitting 5S fragment into two monovalent fragments (3.5S) markedly reduced capacity to provoke anaphylaxis.
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