Antibody to Rat Kidney: In vivo Effects of Univalent and Divalent Fragments
作者： J. H. Baxter , P. A. Small
DOI: 10.1126/SCIENCE.140.3574.1406
关键词: Pepsin 、 Rat kidney 、 Antibody fragments 、 Divalent 、 Antibody 、 Molecular biology 、 Biochemistry 、 Proteinuria 、 In vivo 、 Chemistry 、 Papain
摘要: Whereas intact antibody to rat kidney (7 S ) produced immediate and sustained proteinuria in rats, univalent fragments (papain digests) of the did not, divalent (pepsin only transitory proteinuria. The differed from fixing little, if any, complement vivo which may explain why they not cause serious renal damage.
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