Bioinformatics for high throughput sequencing

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DOI: 10.1007/978-1-4614-0782-9

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摘要: Preface.- Introduction.- Overview of Sequencing Technology Platforms.- Applications High Throughput Sequencing.- Computational Infrastructure and Basic Data Analysis for High-Throughput Base-Calling Bioinformaticians.- De Novo Short Read Assembly.- Mapping.- DNA-Protein Interaction (ChIP-Seq).- Genome-wide Methylation Maps.- Differential Expression RNA (RNA-seq) Data: Mapping, Summarization, Statistical Experimental Design.- MicroRNA Profiling Discovery.- Dissecting Splicing-Regulatory Network by Integrative HITS-CLIP data.- Metagenomics Data.- Software: Current State Future Developments.- Index.

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