Safety of efavirenz in first-trimester of pregnancy: a systematic review and meta-analysis of outcomes from observational cohorts

作者: Nathan Ford , Lynne Mofenson , Katharina Kranzer , Lanre Medu , Lisa Frigati

DOI: 10.1097/QAD.0B013E32833A2A14

关键词:

摘要: … relative risk of termination 5.73 times higher (95% CI 1.45- 22.75%; P = 0.0017) among women exposed to efavirenz compared with other antiretroviral drugs; termination requests were …

参考文章(28)
C. M. Hutamo, G. S. Gericke, A. L. Christianson, M. P. Makhura, P. A. Venter, Congenital anomalies in rural black South African neonates--a silent epidemic? South African Medical Journal. ,vol. 85, pp. 15- 20 ,(1995)
Theresa M. Rossouw, Quantifying antiretroviral risk in pregnancy. South African Medical Journal. ,vol. 97, ,(2007)
Hermann Bussmann, C William Wester, Carolyn N Wester, Bright Lekoko, Okechukwu Okezie, Ann Muir Thomas, S M. Victor DeGruttola, Joseph Makhema, Max Essex, Richard G Marlink, Pregnancy rates and birth outcomes among women on efavirenz-containing highly active antiretroviral therapy in Botswana. Journal of Acquired Immune Deficiency Syndromes. ,vol. 45, pp. 269- 273 ,(2007) , 10.1097/QAI.0B013E318050D683
Akihiko Saitoh, Andrew D Hull, Patricia Franklin, Stephen A Spector, Myelomeningocele in an infant with intrauterine exposure to efavirenz. Journal of Perinatology. ,vol. 25, pp. 555- 556 ,(2005) , 10.1038/SJ.JP.7211343
Claire L Townsend, Barbara A Willey, Mario Cortina-Borja, Catherine S Peckham, Pat A Tookey, Antiretroviral therapy and congenital abnormalities in infants born to HIV-infected women in the UK and Ireland, 1990-2007. AIDS. ,vol. 23, pp. 519- 524 ,(2009) , 10.1097/QAD.0B013E328326CA8E
J Rankin, S Pattenden, L Abramsky, P Boyd, H Jordan, D Stone, M Vrijheid, D Wellesley, Helen Dolk, Prevalence of congenital anomalies in five British regions, 1991–99 Archives of Disease in Childhood-fetal and Neonatal Edition. ,vol. 90, pp. 374- 379 ,(2005) , 10.1136/ADC.2003.047902
Jean B Nachega, Michael Hislop, David W Dowdy, Joel E Gallant, Richard E Chaisson, Leon Regensberg, Gary Maartens, Efavirenz versus nevirapine-based initial treatment of HIV infection: clinical and virological outcomes in Southern African adults. AIDS. ,vol. 22, pp. 2117- 2125 ,(2008) , 10.1097/QAD.0B013E328310407E
V. Jeantils, M.-A. Khuong, J.-L. Delassus, P. Honoré, B. Taverne, M. Uzan, S. Tassi, Grossesse sous efavirenz (Sustiva®) : à propos de 12 cas de patientes positives pour le VIH Gynécologie Obstétrique & Fertilité. ,vol. 34, pp. 593- 596 ,(2006) , 10.1016/J.GYOBFE.2006.04.011
Esau C Joao, Guilherme A Calvet, Margot R Krauss, Laura Freimanis Hance, Javier Ortiz, Silvina A Ivalo, Russell Pierre, Mary Reyes, D Heather Watts, Jennifer S Read, NISDI Perinatal Study Group, Maternal Antiretroviral Use during Pregnancy and Infant Congenital Anomalies: The NISDI Perinatal Study Journal of Acquired Immune Deficiency Syndromes. ,vol. 53, pp. 176- 185 ,(2010) , 10.1097/QAI.0B013E3181C5C81F