Differences of blood pressure estimates between consecutive measurements on one occasion: implications for inter-study comparability of epidemiologic studies.

摘要: Currently, substantial variation in epidemiologic studies exists regarding the number of blood pressure (BP) readings obtained and way which they are combined. This might result systematically different BP estimates. We therefore analysed data from 25,891 subjects (10,124 men 15,767 women) EPIC-Potsdam Study (European Prospective Investigation into Cancer Nutrition) to estimate magnitude differences between consecutive their combinations. Three measurements with 2 min intervals were performed sitting position on right arm supported elevated at heart level by trained interviewers using oscillometric devices. Mean declined first second reading further third systolic 5.0/0.9 mmHg 4.9/0.8 women diastolic 1.5/0.3 1.9/0.5 women, as well pulse (PP) (3.5/0.6 men, 3.0/0.3 hypertension prevalence (9.1/1.7%-points). The decline depended level, age, body mass index (BMI), medication. Combinations including lead generally higher estimates than subsequent or combination. Published mean BP, PP depend handling introduce bias comparison unless same defined used. combination seems be favourable over any single other