Purification of plasminogen

摘要: The purification of plasminogen from human and non-human mammalian plasma or Cohn Fraction III by modified affinity chromotography using Sepharose-L-lysine with high ionic strength buffer solutions as in ion exchange chromatography is described. A produced great yield having unexpectedly enhanced activity toward N.sup.α-CBZ-L-lysine p-nitrophenyl ester, fibrinolytic significantly less contamination unknown colloidal substances.