摘要: This review focuses on biological and molecular properties of defective interfering (DI) particles the rhabdoviruses, but coverage DI other RNA viruses is frequently included to emphasize common principles, significant difference, or phenomena that have not yet been observed examined among rhabdoviruses. Nearly all definitive studies rhabdovirus carried out with prototype rhabdovirus, vesicular stomatitis virus (VSV), VSV are probably most studied best understood particles. Space limitations prevent complete DI-particle field, reader referred earlier reviews for supplemental background information (Huang Baltimore, 1977; Reichmann Schnitzlein, 1979, 1980; Holland et al., Perrault, 1981; Lazzarini Blumberg Kolakofsky, 1983).*