Aortic Stiffness Is an Independent Predictor of Progression to Hypertension in Nonhypertensive Subjects

作者: John Dernellis , Maria Panaretou

DOI: 10.1161/01.HYP.0000157818.58878.93

关键词:

摘要: Aortic stiffness may predict progression to hypertension beyond classic risk factors. In a longitudinal study, we assessed the predictive value of aortic on future in nonhypertensive subjects with blood pressure (BP) <140/90. was determined by echocardiography at baseline 2512 subjects. The follow-up time 4 years. A stepwise increase incidence occurred across male and older participants: 3.8% young female individuals, 11.5% male, 26.1% old female, 58.8% progressed over multivariate analysis, stain, distensibility, index (β) remained significantly associated after adjustment factors men women populations. This study provides first direct evidence our knowledge that is an independent predictor individuals.

参考文章(24)
Barbara G Tabachnick, Linda S Fidell, Jodie B Ullman, None, Using multivariate statistics ,(1983)
C. STEFANADIS, C. STRATOS, H. BOUDOULAS, C. KOUROUKLIS, P. TOUTOUZAS, Distensibility of the ascending aorta: comparison of invasive and non-invasive techniques in healthy men and in men with coronary artery disease European Heart Journal. ,vol. 11, pp. 990- 996 ,(1990) , 10.1093/OXFORDJOURNALS.EURHEARTJ.A059639
Stella Brili, John Dernellis, Constadina Aggeli, Christos Pitsavos, Costas Hatzos, Christodoulos Stefanadis, Pavlos Toutouzas, Aortic elastic properties in patients with repaired coarctation of aorta. American Journal of Cardiology. ,vol. 82, pp. 1140- 1143 ,(1998) , 10.1016/S0002-9149(98)00575-X
Christodoulos Stefanadis, John Dernellis, Eleftherios Tsiamis, Leonidas Diamantopoulos, Andreas Michaelides, Pavlos Toutouzas, Assessment of Aortic Line of Elasticity Using Polynomial Regression Analysis Circulation. ,vol. 101, pp. 1819- 1825 ,(2000) , 10.1161/01.CIR.101.15.1819
T. KAWASAKI, S. SASAYAMA, S.-I. YAGI, T. ASAKAWA, T. HIRAI, Non-invasive assessment of the age related changes in stiffness of major branches of the human arteries Cardiovascular Research. ,vol. 21, pp. 678- 687 ,(1987) , 10.1093/CVR/21.9.678
Duanping Liao, Donna K. Arnett, Herman A. Tyroler, Ward A. Riley, Lloyd E. Chambless, Moyses Szklo, Gerardo Heiss, Arterial Stiffness and the Development of Hypertension: The ARIC Study Hypertension. ,vol. 34, pp. 201- 206 ,(1999) , 10.1161/01.HYP.34.2.201
Silja Majahalme, Väinö Turjanmaa, Alan B. Weder, Hong Lu, Martti T. Tuomisto, Arto Uusitalo, Blood Pressure Level and Variability in the Prediction of Blood Pressure After 5-Year Follow-up Hypertension. ,vol. 28, pp. 725- 731 ,(1996) , 10.1161/01.HYP.28.5.725
Ramachandran S Vasan, Martin G Larson, Eric P Leip, William B Kannel, Daniel Levy, Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study. The Lancet. ,vol. 358, pp. 1682- 1686 ,(2001) , 10.1016/S0140-6736(01)06710-1