Alterations in Protein and Nucleic Acid Metabolism of Thymocytes Produced by Adrenal Steroids in Vitro
作者： Maynard H. Makman , B. Dvorkin , Abraham White
DOI: 10.1016/S0021-9258(18)96761-X
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摘要: Abstract Thymocytes from cortisol-treated rats, incubated in vitro, showed a lower incorporation of radioactive precursors into ribonucleic acid, deoxyribonucleic and protein than did cells control animals. Thymolytic steroids present vitro at concentrations 10-10 m to 10-5 the thymocyte suspensions caused similar inhibitions. Good correlation was found between relative potency tested their reported assessed vivo.
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