Hypervalent Iodine‐Mediated Aziridination of Alkenes: Mechanistic Insights and Requirements for Catalysis

摘要: By detailed study of the possible side reactions in previously reported aziridination alkenes with N-aminoheterocycles mediated by hypervalent iodine reagents, requirements to make this reaction catalytic iodoarene have been determined. The requires an oxidant that will oxidise iodoarenes but does not alkenes, it is no such actually exists! A method which reagent can be recycled without need for reisolation possible. Further into mechanism gives tentative evidence proceeds through formation aminoiodane reacts directly alkene, contrary previous literature reports acetoxyamine intermediate suggested. temperature effect remarkable.