IgE IN GLOMERULI OF PATIENTS WITH NEPHROTIC SYNDROME

作者: MichaelA. Gerber , Fiorenzo Paronetto

DOI: 10.1016/S0140-6736(71)91838-1

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摘要: Abstract Localisation of IgE was investigated by fluorescent-antibody technique in the kidneys thirteen patients with nephrotic syndrome. In seven nine minimal changes, demonstrated glomerular capillary walls a " comma-like pattern absence IgG, IgM, IgA, and complement. The extent glomeruli corresponded to degree proteinuria, which notably reduced four who had been treated steroids before biopsy. Four syndrome diagnosis focal sclerosing lesions, membranous nephropathy, or advanced chronic glomerulonephritis exhibited prominent deposition granular segmental linear walls. three these IgG complement were also detected glomeruli. These findings suggest that plays role pathogenesis some forms

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