A novel water-soluble near-infrared glucose-conjugated porphyrin: synthesis, properties and its optical imaging effect
作者： Feng Lv , Xujun He , Li Lu , Li Wu , Tianjun Liu
DOI: 10.1142/S1088424611003252
关键词:
摘要: A simple novel near-infrared water-soluble glucose-conjugated porphyrin, 5,15-bis-[(trimethylsilyl)ethynyl]-10,20-bis[4-β-D-glucopyranosyl)phenyl]porphyrin, with good optical stability and high emission ability in region, was synthesized. And Optical Imaging vivo this compound as probe performed on liver tumor-bearing nude mice. The result shows that porphyrin could display information more than 1 cm depth, which implies its potential application cancer diagnosis.
sci-hub.se 参考文章(19)
Hisataka Kobayashi, Mikako Ogawa, Raphael Alford, Peter L. Choyke, Yasuteru Urano, New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging Chemical Reviews. ,vol. 110, pp. 2620- 2640 ,(2010) , 10.1021/CR900263J
Xunjin Zhu, Shitao Fu, Wai-Kwok Wong, Wai-Yeung Wong, A near-infrared fluorescent chemodosimeter for silver(I) ion based on an expanded porphyrin Tetrahedron Letters. ,vol. 49, pp. 1843- 1846 ,(2008) , 10.1016/J.TETLET.2008.01.037
Natalie A. Christian, Fabian Benencia, Michael C. Milone, Guizhi Li, Paul R. Frail, Michael J. Therien, George Coukos, Daniel A. Hammer, In vivo dendritic cell tracking using fluorescence lifetime imaging and near-infrared-emissive polymersomes. Molecular Imaging and Biology. ,vol. 11, pp. 167- 177 ,(2009) , 10.1007/S11307-008-0184-X
Cheng-Kang Chiang, Chih-Ching Huang, Chi-Wei Liu, Huan-Tsung Chang, Oligonucleotide-based fluorescence probe for sensitive and selective detection of mercury(II) in aqueous solution. Analytical Chemistry. ,vol. 80, pp. 3716- 3721 ,(2008) , 10.1021/AC800142K
Xin Chen, Li Hui, David A. Foster, Charles Michael Drain, Efficient synthesis and photodynamic activity of porphyrin-saccharide conjugates: targeting and incapacitating cancer cells. Biochemistry. ,vol. 43, pp. 10918- 10929 ,(2004) , 10.1021/BI049272V
Johannes M. Kroon, Ernst J. R. Sudhoelter, Albertus P. H. J. Schenning, Roeland J. M. Nolte, Self-Organization of Amphiphilic Porphyrins at the Air-Water-Interface Langmuir. ,vol. 11, pp. 214- 220 ,(1995) , 10.1021/LA00001A037
Scott A Hilderbrand, Ralph Weissleder, Near-infrared fluorescence: application to in vivo molecular imaging Current Opinion in Chemical Biology. ,vol. 14, pp. 71- 79 ,(2010) , 10.1016/J.CBPA.2009.09.029
Eishun Tsuchida, Keitaro Sou, Akito Nakagawa, Hiromi Sakai, Teruyuki Komatsu, Koichi Kobayashi, Artificial oxygen carriers, hemoglobin vesicles and albumin-hemes, based on bioconjugate chemistry. Bioconjugate Chemistry. ,vol. 20, pp. 1419- 1440 ,(2009) , 10.1021/BC800431D
P. P. Ghoroghchian, P. R. Frail, K. Susumu, D. Blessington, A. K. Brannan, F. S. Bates, B. Chance, D. A. Hammer, M. J. Therien, Near-infrared-emissive polymersomes: Self-assembled soft matter for in vivo optical imaging Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 2922- 2927 ,(2005) , 10.1073/PNAS.0409394102
Yu Cao, Anila Fiaz Gill, Dabney W. Dixon, Synthesis and characterization of a water-soluble porphyrin with a cyclic sulfone Tetrahedron Letters. ,vol. 50, pp. 4358- 4360 ,(2009) , 10.1016/J.TETLET.2009.05.039