A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f u,cell )

作者: Andrea Treyer , Sandra Walday , Hinnerk Boriss , Pär Matsson , Per Artursson

DOI: 10.1007/S11095-019-2717-1

关键词:

摘要: PurposeThe intracellular fraction of unbound compound (f(u,cell)) is an important parameter for accurate prediction drug binding to targets. f(u,cell) the result a passive di ...

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