Circulating tumor markers.

摘要: The concept of a circulating tumor marker applies to secreted chemical product cell such that the concentration in blood may some way represent quantifiable assessment burden at time. Probably earliest examples were proteins produced from myeloma cells discovered by Bence Jones mid-19th century. Currently range possible markers is broad; however, relatively few have been incorporated routine oncologic practice (Table 1). clinical roles might include screening; diagnosis; staging; prognosis; and monitoring response, remission, relapse. Additionally, as specific products, substances confer tissue specificity for immunohistochemistry (IHC) antibody (Ab)-based techniques imaging therapy.