Management of type 2 diabetes with multiple oral hypoglycaemic agents or insulin in primary care: Retrospective cohort study

摘要: Background Intensive glycaemic control can reduce the risk of microvascular complications in people with type 2 diabetes. Aim To examine extent monitoring and patients diabetes prescribed oral agents and/or insulin, to investigate transition insulin. Design study Retrospective cohort study. Setting A total 154 general practices UK contributing DIN-LINK database between 1995 2005. Method People were identified using Read codes prescribing data. Outcome measures were: on multiple Results 14 824 concurrently, whom 5064 (34.16%) had haemoglobin 1c (HbA ) assessments 6 months before following initiation their last therapy. Mean HbA therapy was 9.07%, which dropped 8.16% (mean difference 0.91%, 95% confidence interval [CI] = 0.86 0.95, P assessments, 3153 (62.26%) evidence poor Median time insulin for 7.7 years (95% CI 7.4 8.5 years); 1513 began during 9.85% (standard deviation [SD] 1.96%) decreased by 1.34%, 1.24% 1.44%) therapy, but 1110 (73.36%) still ≥7.5%. Conclusion Many received inadequate control. management is required complications.