End-stage renal disease in North Africa

摘要: End-stage renal disease in North Africa. There are many similarities the profile of chronic five African countries, reflecting their close resemblance ethnic background, bioecology and socioeconomic standards. The incidence is much higher than that West, yet prevalence relatively lower, which mirrors inadequacy medical care facilities. principal causes end-stage (ESRD) interstitial nephritis (14 to 32%), often attributed environmental pollution inadvertent use medications; glomerulonephritis (11 24%), mostly mesangioproliferative focal segmental sclerosis; diabetes (5 20%) nephrosclerosis 21%). Obstructive/reflux nephropathy, urinary schistosomiasis, common Egypt (7%), Libya Southern Algeria. Primary urolithiasis a frequent cause obstructive nephropathy western (hyperoxaluria) middle (cystinuria) regions. tuberculosis increasing, particularly diffuse hematogenous forms. It responsible also for 10 40% amyloidosis. latter frequently associated with familial Mediterranean fever. Sickle cell anemia an important health problem west, leading wide range glomerular tubulointerstitial nephropathies. Takayasu increasingly recognized as ischemic renovascular hypertension. management ESRD largely influenced by late referral, co-morbidities lack dialysis Hemodialysis most modality replacement therapy (RRT). CAPD used sporadically. Renal transplantation, from live (often unrelated) donors, offered less 5% patients ESRD. reported outcome RRT generally conforms international