Termination of pregnancy by sheep anti-LHRH gamma globulin in rats

摘要: The effect of the administration sheepanti-LHRH γ-globulin (anti-LHRHG) onthe maintenanceof pregnancy was investigated in rats. Nidation confirmed by laparotomy on day 7 or8 pregnancy. In one experiment, rats were theninjected iv with 1 ml anti-LHRHG or normal sheep-γ-globulin (NSG) daily from days to 11. uteriwere inspected again 14 pregnancy, whenit found that complete resorption fetuseshad occurred anti-LHRHG-treated rats, butthat fetuses NSG-treatedcontrol a single injection mlof 7, 8, 9, 10, 11, 12 ofpregnancy also investigated. Administration onday 9 10 resulted thefetuses time the2nd inspection 14, and treatment 8 11 partially effective. However, exerted littleeffect viability fetuses. None ratsshowed vaginal bleeding following withanti-LHRHG. Termination an...