Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells
作者： Chi Ma , Miaojun Han , Bernd Heinrich , Qiong Fu , Qianfei Zhang
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摘要: INTRODUCTION Primary liver tumors and liver metastasis currently represent the leading cause of cancer-related deaths. The liver intimately cross-talks with the gut and performs many …
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Andreas Limmer, Jutta Ohl, Christian Kurts, Hans-Gustaf Ljunggren, Yuval Reiss, Marcus Groettrup, Frank Momburg, Bernd Arnold, Percy A. Knolle, Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance. Nature Medicine. ,vol. 6, pp. 1348- 1354 ,(2000) , 10.1038/82161
Masaki Terabe, Jay A. Berzofsky, The role of NKT cells in tumor immunity. Advances in Cancer Research. ,vol. 101, pp. 277- 348 ,(2008) , 10.1016/S0065-230X(08)00408-9
T. Olszak, D. An, S. Zeissig, M. P. Vera, J. Richter, A. Franke, J. N. Glickman, R. Siebert, R. M. Baron, D. L. Kasper, R. S. Blumberg, Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function Science. ,vol. 336, pp. 489- 493 ,(2012) , 10.1126/SCIENCE.1219328
Aurélien Marabelle, Holbrook Kohrt, Idit Sagiv-Barfi, Bahareh Ajami, Robert C. Axtell, Gang Zhou, Ranjani Rajapaksa, Michael R. Green, James Torchia, Joshua Brody, Richard Luong, Michael D. Rosenblum, Lawrence Steinman, Hyam I. Levitsky, Victor Tse, Ronald Levy, Depleting tumor-specific Tregs at a single site eradicates disseminated tumors Journal of Clinical Investigation. ,vol. 123, pp. 2447- 2463 ,(2013) , 10.1172/JCI73340
Takeshi Shimaoka, Noriaki Kume, Manabu Minami, Kazutaka Hayashida, Hiroharu Kataoka, Toru Kita, Shin Yonehara, Molecular Cloning of a Novel Scavenger Receptor for Oxidized Low Density Lipoprotein, SR-PSOX, on Macrophages Journal of Biological Chemistry. ,vol. 275, pp. 40663- 40666 ,(2000) , 10.1074/JBC.C000761200
Fran Balkwill, Cancer and the chemokine network Nature Reviews Cancer. ,vol. 4, pp. 540- 550 ,(2004) , 10.1038/NRC1388
Charlie G. Buffie, Vanni Bucci, Richard R. Stein, Peter T. McKenney, Lilan Ling, Asia Gobourne, Daniel No, Hui Liu, Melissa Kinnebrew, Agnes Viale, Eric Littmann, Marcel R. M. van den Brink, Robert R. Jenq, Ying Taur, Chris Sander, Justin R. Cross, Nora C. Toussaint, Joao B. Xavier, Eric G. Pamer, Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile Nature. ,vol. 517, pp. 205- 208 ,(2015) , 10.1038/NATURE13828
Amala Alag, Tejas Kadakia, Tom M McCaughtry, Motoko Y Kimura, Susan O Sharrow, Terry I Guinter, Lionel Feigenbaum, Alfred Singer, Leonid A Pobezinsky, Ruth Etzensperger, Susanna Jeurling, Let-7 microRNAs target the lineage-specific transcription factor PLZF to regulate terminal NKT cell differentiation and effector function. Nature Immunology. ,vol. 16, pp. 517- 524 ,(2015) , 10.1038/NI.3146
You Jeong Lee, Keli L Holzapfel, Jinfang Zhu, Stephen C Jameson, Kristin A Hogquist, Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells Nature Immunology. ,vol. 14, pp. 1146- 1154 ,(2013) , 10.1038/NI.2731
Chang H. Kim, Eric J. Kunkel, Judie Boisvert, Brent Johnston, James J. Campbell, Mark C. Genovese, Harry B. Greenberg, Eugene C. Butcher, Bonzo/CXCR6 expression defines type 1–polarized T-cell subsets with extralymphoid tissue homing potential Journal of Clinical Investigation. ,vol. 107, pp. 595- 601 ,(2001) , 10.1172/JCI11902