Evaluation of the actions of general anaesthetics in the human brain

摘要: Abstract 1. General anaesthesia is a state of analgesia and impaired cognitive function that results from the depressant effects anaesthetics. 2. Graded increases in anaesthetic concentration cause progressive impairment function, extremes which are commonly described as “light” “deep” anaesthesia. 3. Surgical stimulation produces activation EEG may arouse patient deeper to lighter function. 4. It be very difficult, particularly patients with neuromuscular blockade, identify change conscious awareness. 5. A range methods has been used for evaluating depth 6. The evidence reviewed this paper suggests median frequency auditory evoked potential appear best techniques monitoring graded anaesthetics on brain. 7. frequency, 10 Hz subjects, should kept below 5 during ensure there no response verbal command. 8. measures resulting depression surgical “depth anaesthesia”. 9. However it not yet certain whether particular feature e.g. Nb latency, or collection features between 20 80 msec gives most reliable index