Antiviral activity of 2-amino-4, 4α-Dihydro-4α-7-dimethyl-3H-phenoxazine-3-one on poliovirus

作者: Akiko Iwata , Teruhide Yamaguchi , Kouei Sato , Ryutaro Izumi , Akio Tomoda

DOI: 10.1620/TJEM.200.161

关键词:

摘要: 2-Amino-4, 4α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one (Phx), which was produced by the reaction of bovine hemoglobin with 2-amino-5-methylphenol, inhibited proliferation poliovirus in Vero cells between 0.25 μg-/ml and 2 maximal antiviral acitivity at 1 μg-/ml. These results suggest that Phx may be useful to prevent infection.

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