In patients with head injury undergoing rapid sequence intubation, does pretreatment with intravenous lignocaine/lidocaine lead to an improved neurological outcome? A review of the literature.

摘要: It is well known that laryngeal instrumentation and endotracheal intubation associated with a marked, transient rise in intracranial pressure (ICP). Patients head injury requiring are considered particularly at risk from this ICP as it reduces cerebral perfusion thus may increase secondary brain injury. The favoured method for securing definitive airway patient group by rapid sequence (RSI). In the United States Emergency Airway Course teaches emergency physicians to routinely administer intravenous lidocaine pre treatment RSI an attempt attenuate ICP. A literature search was carried out identify studies which used pretreatment major Any link improved neurological outcome also sought. Papers identified were appraised manner recommended evidence based medicine ensure validity. There no answered our question directly and, furthermore, belief such study, present, exists literature. Six valid papers found, individually contained elements of posed these presented narrative graphic form. currently support use patients its should only occur clinical trials.