Further Enhancement of Intraocular Open-Capsule Devices for Prevention of Posterior Capsule Opacification

作者: Lee Slutzky , Guy Kleinmann

DOI: 10.1167/TVST.7.1.21

关键词:

摘要: Purpose We improve the intraocular open-capsule devices (IOCD) for prevention of posterior capsule opacification (PCO). Methods A total 45 New Zealand rabbit eyes were divided into six similar groups after crystalline lens evacuation. Each group was implanted with a hydrophilic (IOL) and IOCD different designs. In first experiment (Part A), square design ring without large apertures compared to round apertures. second B), IOCDs small high low density. PCO Soemmering's evaluated clinically, by Miyake Apple view, histologically. The results control IOL only. Results All showed significant group. Part A: had lowest level peripheral epithelial cells proliferation (protrusions). B: modifying size density no influence on those protrusions. Conclusions significantly reduced rate its precursor, ring. rings edges produced best results. study underpowered determine design. Translational Relevance has potential prevent up 80% cases; most common complication cataract surgery. is important success.

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