Changes in the Gallus gallus Proteome Induced by Marek’s Disease Virus

摘要: Marek’s disease virus (MDV) is a highly oncogenic avian herpesvirus. We have used modified MudPIT analysis to examine the effect of MDV infection on chicken proteome. identified 3561 unique nonphosphorylated peptides, representing 1460 proteins, in mock-infected sample versus 4240 1676 an MDV-infected sample. Of these 59.1% from mock- and 49.6% samples were detected both samples, for represented 69.1% 60.2% common samples. In terms phosphorylation, 357 506 phosphopeptides, 342 483 respectively. At phosphopeptide level, 10.1% 7.1% overlapped, phosphoproteins, 12.0% 8.5% sampl...