Alt a 1 allergen homologs from Alternaria and related taxa: analysis of phylogenetic content and secondary structure

作者: Soon Gyu Hong , Robert A. Cramer , Christopher B. Lawrence , Barry M. Pryor

DOI: 10.1016/J.FGB.2004.10.009

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摘要: A gene for the Alternaria major allergen, Alt a 1, was amplified from 52 species of Alternaria and related genera, and sequence information was used for phylogenetic study. Alt a 1 gene sequences evolved 3.8 times faster and contained 3.5 times more parsimony-informative sites than glyceraldehyde-3-phosphate dehydrogenase (gpd) sequences. Analyses of Alt a 1 gene and gpd exon sequences strongly supported grouping of Alternaria spp. and related taxa into several species-groups described in previous studies, especially the infectoria …

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