Optimising outcomes for patients with early inflammatory arthritis

摘要: Background: Early and effective treatment of inflammatory arthritis (IA) is essential to preserve patients’ functional ability prevent joint damage. Recent strategies for optimising care have included implementing target management utilising ultrasound guide decisions. The 2010 ACR/EULAR rheumatoid (RA) classification criteria were also recently developed with the aim facilitating study early IA. Aims: To determine phenotype, outcomes patients IA, defined using RA criteria, in clinical practice. Specific objectives risk stratify according future disease severity, their response assess potential utility within a strategy. Methods: An audit prospective longitudinal observational conducted attending Leeds Arthritis Clinic. Patients classified as undifferentiated (UA) or at baseline. Logistic regression methods used identify baseline predictors outcome response. Results: Ultrasound detectable synovitis was independently associated higher rate methotrexate use, persistence IA development new erosions one year UA RA, well progression from subset A lack concordance observed between determined remission receiving treatment-to-target management. In this sub-group, objective measures predictive imaging comparison predominantly subjective parameters, which remission. Conclusions: This verifies value prognostic tool stratification over above application assessments. It supports research use strategy.