BBB transport and P-glycoprotein functionality using MDR1A (-/-) and wild-type mice. Total brain versus microdialysis concentration profiles of rhodamine-123.

作者: Elizabeth C. M. de Lange , Gertjan de Bock , Alfred H. Schinkel , Albertus G. de Boer , Douwe D. Breimer

DOI: 10.1023/A:1011988024295

关键词:

摘要: Purpose. The effect of P-glycoprotein (Pgp) on brain distribution using mdrla (-/-) mice was investigated.

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