Recovery and Calibration Techniques: Toward Quantitative Microdialysis

摘要: One of the most important questions in microdialysis is how to relate concentrations microdialysate true outside probe as vitro recovery was not equal per se vivo. Many calibration techniques and approaches have been proposed, with different levels practicality usefulness, obtain quantitative information on extracellular a function time. Today, we build up enough experience know data using technique. With that, it only technique that provides unbound concentration compounds fluid spaces body, being highly drug development are drivers for effect.