作者: Xianglin L. Du , Shenying Fang , Sally W. Vernon , Hashem El-Serag , Y. Tina Shih
DOI: 10.1002/CNCR.22826
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摘要: BACKGROUND. To the authors' knowledge, few studies have addressed racial disparities in survival of patients with colon cancer by adequately incorporating treatment and socioeconomic factors addition to patient tumor characteristics. METHODS. The authors studied a nationwide population-based, retrospective cohort 18,492 men women who were diagnosed stage II or III at age ≥65 years between 1992 1999. This was identified from Surveillance, Epidemiology, End Results (SEER) registries-Medicare linked databases included up 11 follow-up. RESULTS. A larger proportion (70%) African-American fell into poorest quartiles status compared Caucasians (21%). Patients lived communities lowest level had 19% higher all-cause mortality highest (hazards ratio [HR], 1.19; 95% confidence interval [95% CI], 1.13–1.26; P < .001 for trend). The risk dying reduced only slightly after controlling race/ethnicity (HR, 1.17; CI, 1.10–1.24). Compared Caucasian cancer, 21% more likely die age, sex, comorbidity scores, stage, grade 1.21; 1.12–1.30). After also adjusting definitive therapy status, HR marginally significantly African Americans 1.10; 1.02–1.19) cancer-specific 1.16; 1.01–1.33). CONCLUSIONS. Lower lack associated strongly decreased both cancer. Racial explained substantially differences status. Cancer 2007. © 2007 American Society.