作者: James Symanowski , Paulo S. Pinheiro , Lucas N. Wassira , Alicia Hansen
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摘要: BACKGROUND: Substantial disparities in colorectal cancer (CRC) survival among racial-ethnic groups, especially between Blacks and Whites, have been extensively documented the Northeast, California South of United States. The purpose this study was to ascertain determinants a state Mountain West region, Nevada. METHODS: population consisted cohort 12,181 men women with first primary invasive carcinoma colon rectum diagnosed 1995 2007, identified through Nevada Central Cancer Registry followed for vital status until 31 December 2007. Likelihood ratio chi-square statistics were used compare sociodemographic clinical characteristics race-ethnicity. Cox proportional regression modeling partial likelihood tests estimate hazard ratios assess interaction effects CRC cause-specific death. RESULTS: Hispanics more likely be distant stage disease, 22.4% 21.5% respectively, compared 17.9% Whites. No difference observed groups diagnoses regional stage. Univariate analysis yielded 20.1% higher risk death Whites [95% CI = 1.05-1.37]. Adjustment tumor stage, sex, age, diagnosis period, sublocation, marital status, economic multivariate model showed persistently increased (HR 1.17, 95% 1.02-1.33) relation CONCLUSIONS AND IMPLICATIONS: Survival persisted our even after adjusting common demographic factors. Further race/ethnicities, such as course treatment, should investigated. Additionally, public health intervention programs tailor screening awareness towards minorities well ensuring equal access care quality treatment. Ethn Dis. 2013;23[1]:103–109