Contacts Between Alcohols in Water Are Random Rather than Hydrophobic

摘要: Given the importance of water-mediated hydrophobic interactions in a wide range biological and synthetic self-assembly processes, it is remarkable that both sign magnitude between simple amphiphiles, such as alcohols, remain unresolved. To address this question, we have performed Raman hydration-shell vibrational spectroscopy polarization-resolved femtosecond infrared experiments, well random mixing molecular dynamics simulations. Our results indicate there are no more contacts aqueous solutions alcohols ranging from methanol to tertiary butyl alcohol than mixtures same concentration. This implies interaction small groups weaker thermal energy fluctuations. Thus, corresponding must be repulsive, with sufficient negate attractive direct van der Waals groups.