Atomic structures at last: the ribosome in 2000.

作者: V Ramakrishnan , P.B Moore

DOI: 10.1016/S0959-440X(00)00184-6

关键词:

摘要: Last year, atomic structures of the 50S ribosomal subunit from Haloarcula marismortui and 30S Thermus thermophilus were published. A year before that, a 7.8 resolution electron density map 70S ribosome T. appeared. This information is revolutionizing our understanding protein synthesis.

参考文章(58)
Yonath A, Makowski I, Gewitz Hs, Wittmann Hg, Arad T, Müssig J, Glotz C, Three-dimensional crystals of ribosomes and their subunits from eu- and archaebacteria. Biochemistry international. ,vol. 15, pp. 953- ,(1987)
Thomas V. O'Halloran, Stephen J. Lippard, Timothy J. Richmond, Aaron Klug, Multiple heavy-atom reagents for macromolecular X-ray structure determination. Application to the nucleosome core particle. Journal of Molecular Biology. ,vol. 194, pp. 705- 712 ,(1987) , 10.1016/0022-2836(87)90248-8
Rajendra K. Agrawal, Amy B. Heagle, Pawel Penczek, Robert A. Grassucci, Joachim Frank, EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome. Nature Structural & Molecular Biology. ,vol. 6, pp. 643- 647 ,(1999) , 10.1038/10695
Joachim Frank, Rajendra Kumar Agrawal, A ratchet-like inter-subunit reorganization of the ribosome during translocation. Nature. ,vol. 406, pp. 318- 322 ,(2000) , 10.1038/35018597
Nenad Ban, Poul Nissen, Jeffrey Hansen, Malcolm Capel, Peter B. Moore, Thomas A. Steitz, Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit. Nature. ,vol. 400, pp. 841- 847 ,(1999) , 10.1038/23641
William M. Clemons, Joanna L. C. May, Brian T. Wimberly, John P. McCutcheon, Malcolm S. Capel, V. Ramakrishnan, Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution. Nature. ,vol. 400, pp. 833- 840 ,(1999) , 10.1038/23631
D. Fourmy, M. I. Recht, S. C. Blanchard, J. D. Puglisi, Structure of the A Site of Escherichia coli 16S Ribosomal RNA Complexed with an Aminoglycoside Antibiotic Science. ,vol. 274, pp. 1367- 1371 ,(1996) , 10.1126/SCIENCE.274.5291.1367
Florian Mueller, Ingolf Sommer, Pavel Baranov, Rishi Matadeen, Matthias Stoldt, Jens Wöhnert, Matthias Görlach, Marin van Heel, Richard Brimacombe, The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 A resolution. Journal of Molecular Biology. ,vol. 298, pp. 35- 59 ,(2000) , 10.1006/JMBI.2000.3635