Isoprostanoid Profiling of Marine Microalgae

摘要: Algae result from a complex evolutionary history that shapes their metabolic network. For example, these organisms can synthesize different polyunsaturated fatty acids, such as those found in land plants and oily fish. Due to the presence of numerous double-bonds, molecules be oxidized nonenzymatically, this results biosynthesis high-value bioactive metabolites named isoprostanoids. So far, there have been only few studies reporting isoprostanoid productions algae. To fill gap, current investigation aimed at profiling isoprostanoids by liquid chromatography -mass spectrometry/mass spectrometry (LC-MS/MS) four marine microalgae. A good correlation was observed between most abundant acids (PUFAs) produced investigated microalgal species profiles. No significant variations content derivatives were for Rhodomonas salina Chaetoceros gracilis under copper stress, whereas increases production C18-, C20- C22-derived monitored Tisochrysis lutea Phaeodactylum tricornutum. In hydrogen peroxide, no changes C. T. lutea, while other two This study paves way further studying physiological roles microalgae exploring bioresources production.