Monoclonal antibodies specific for phf-tau, hybridomas secreting them, antigen recognition by these antibodies and their applications

作者: Marc Vandermeeren , Andre Van De Voorde , Eugeen Vanmechelen

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摘要: The present invention relates more particularly to a monoclonal antibody which forms an immunological complex with phosphorylated epitope of antigen belonging abnormally tau (PHF-tau) residing in the region spanning positions (143-254), and said being characterized by fact that it is capable specifically detecting protein cerebrospinal fluid (CSF).

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