Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes.
作者： Marc Mercken , Marc Vandermeeren , Ursula Lübke , Jan Six , Jef Boons
DOI: 10.1007/BF00227819
关键词: Epitope 、 Tau protein 、 Phosphatase 、 Antibody 、 Alkaline phosphatase 、 Molecular biology 、 Monoclonal antibody 、 Chemistry 、 Blot 、 Phosphorylation
摘要: A modified form of the microtubule-associated protein Tau is the major component of the paired helical filaments (PHF) found in Alzheimer's disease. The characterization of these …
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