Translocation 1;7 in hematologic disorders--a report of three further cases. Absence of amplification of the gene for the epidermal growth factor receptor.

作者: Gail M. Abrahamson , Katrina Rack , Veronica J. Buckle , David G. Oscier , Susan Kelly

DOI: 10.1016/0165-4608(91)90118-E

关键词:

摘要: We report three new cases with a hematologic disorder and the unbalanced translocation der(1)t(1;7)(p11;p11). It has been speculated that gene for epidermal growth factor receptor, localized to short arm of chromosome 7, might be amplified in this translocation. have demonstrated there is no amplification these cases.

参考文章(9)
Pascale Willem, Maximina Pinto, Renee Bernstein, Translocation t(1;7) revisited: Report of three further cases and review☆ Cancer Genetics and Cytogenetics. ,vol. 36, pp. 45- 54 ,(1988) , 10.1016/0165-4608(88)90074-X
Gayle E. Woloschak, Gordon W. Dewald, Rebecca S. Bahn, Robert A. Kyle, Philip R. Greipp, Robert C. Ash, Amplification of RNA and DNA specific for erb B in unbalanced 1;7 chromosomal translocation associated with myelodysplastic syndrome Journal of Cellular Biochemistry. ,vol. 32, pp. 23- 34 ,(1986) , 10.1002/JCB.240320104
Jacques M.J.C. Scheres, Theo W.J. Hustinx, Joep P.M. Geraedts, C.Henk W. Leeksma, Paul S. Meltzer, Translocation 1; 7 in hematologic disorders: a brief review of 22 cases Cancer Genetics and Cytogenetics. ,vol. 18, pp. 207- 213 ,(1985) , 10.1016/0165-4608(85)90085-8
J. Downward, Y. Yarden, E. Mayes, G. Scrace, N. Totty, P. Stockwell, A. Ullrich, J. Schlessinger, M. D. Waterfield, Close similarity of epidermal growth factor receptor and v- erb-B oncogene protein sequences Nature. ,vol. 307, pp. 521- 527 ,(1984) , 10.1038/307521A0
Young-hua Xu, Shunsuke Ishii, Adrian J. L. Clark, Margery Sullivan, Richard K. Wilson, Din Pow Ma, Bruce A. Roe, Glenn T. Merlino, Ira Pastan, Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells. Nature. ,vol. 309, pp. 806- 810 ,(1984) , 10.1038/309806A0
Shigeo Horiike, Masafumi Taniwaki, Shinichi Misawa, Hikari Nishigaki, Tsukasa Okuda, Shohei Yokota, Kei Kashima, Johji Inazawa, Tatsuo Abe, The unbalanced 1;7 translocation inde novo myelodysplastic syndrome and its clinical implication Cancer. ,vol. 65, pp. 1350- 1354 ,(1990) , 10.1002/1097-0142(19900315)65:6<1350::AID-CNCR2820650617>3.0.CO;2-J
J. P. M. Geraedts, G. J. den Ottolander, J. E. Ploem, O. G. Muntinghe, An Identical Translocation between Chromosome 1 and 7 in Three Patients with Myelofibrosis and Myeloid Metaplasia British Journal of Haematology. ,vol. 44, pp. 569- 575 ,(1980) , 10.1111/J.1365-2141.1980.TB08711.X
Tom Maniatis, Joseph Sambrook, E. F. Fritsch, Molecular Cloning: A Laboratory Manual ,(2001)