Translocation t(1;7) revisited: Report of three further cases and review☆

作者: Pascale Willem , Maximina Pinto , Renee Bernstein

DOI: 10.1016/0165-4608(88)90074-X

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摘要: Three white patients, two with myelofibrosis and one refractory anemia, presented a t(1;7). The clinical cytogenetic findings are discussed in the context of 45 cases already published. Rather than specific association t(1;7) particular hematologic disorder, review literature strongly suggests correlation therapeutic or environmental exposure to toxic substances. proposed mechanisms explain origin briefly reviewed.

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