Cyto-protective and immunomodulating effect of Curcuma longa in Wistar rats subjected to carbon tetrachloride-induced oxidative stress.
作者： H. A. Abu-Rizq , M. H. Mansour , A. M. Safer , M. Afzal
DOI: 10.1007/S10787-007-1621-1
关键词:
摘要: A comparison of crude curcuminoid extract and purified curcumin was made to evaluate hepato- immunoprotective effect Curcuma longa (turmeric) Zingiberaceae. Carbon tetrachloride (CCl4) induced cellular hepatic damage evaluated by transmission electron microscopy, enzymes thiobarbituric acid reactive species (TBAR) values. selective cytolytic CCl4 observed among immature (PNA+) thymocytes peripheral helper (CD4+) T lymphocytes in spleen paralleled a significant reduction CD25, CD71 Con receptor expression. Treatment with at two different doses, showed recovery hepatocytes, which reflected TBAR restoration lymphocyte viability expression both splenic observed. Turmeric extract, low high dose, found be more efficient as compared curcumin.
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