Analysis of Quality of Nuchal Translucency Measurements: Its Role in Prenatal Diagnosis

作者: Carmen Comas Gabriel , M. Echevarria , I. Rodríguez , B. Serra

DOI: 10.1100/2012/482832

关键词:

摘要: Objective. Quantitative analysis of the quality nuchal translucency (NT) measurements. Methods. First-trimester combined screening for Down syndrome was performed to all pregnant women attended in our Department from October 2003 November 2009. NT measured according Fetal Medicine Foundation (FMF) criteria by 20 trained obstetricians. The performance measurements retrospectively analyzed with regard several control standards. Accuracy experience, professional profile, crown rump length (CRL) values, and FMF certification statistically tested. Results. A total 14978 were assessed. (1) mean operator-specific median NT-MoM values 0,98. (2) Mean percentage cases >95th <5th centiles 5,0% 4,2%, respectively. (3) Logarithmic SD MoM 0,00 0,13, (4) DR trisomy 21 at time 90,7% a FPR 6,7% standard strategy. (5) According Cumulative SUM (CUSUM) figures, more acceptable FMF-certified operators. Conclusion. Overall, standards show optimal unit. Operator dedicated profile fetal medicine, CRL over 60 mm, have significant positive impact on

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