Recognition of cytosolic DNA by cGAS and other STING-dependent sensors
作者： Numana Bhat , Katherine A. Fitzgerald
关键词:
摘要: … dsDNA and subsequently triggers a cytosolic STING pathway. Studies using p204 siRNA in … of this protein family can engage STING or ASC dependent pathways 48. These findings …
core.ac.uk
sci-hub.se 参考文章(62)
Andrea Ablasser, Marion Goldeck, Taner Cavlar, Tobias Deimling, Gregor Witte, Ingo Röhl, Karl-Peter Hopfner, Janos Ludwig, Veit Hornung, cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING Nature. ,vol. 498, pp. 380- 384 ,(2013) , 10.1038/NATURE12306
Takumi Kawasaki, Taro Kawai, Shizuo Akira, Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity Immunological Reviews. ,vol. 243, pp. 61- 73 ,(2011) , 10.1111/J.1600-065X.2011.01048.X
Sarah A. Stanley, James E. Johndrow, Paolo Manzanillo, Jeffery S. Cox, The Type I IFN response to infection with Mycobacterium tuberculosis requires ESX-1-mediated secretion and contributes to pathogenesis. Journal of Immunology. ,vol. 178, pp. 3143- 3152 ,(2007) , 10.4049/JIMMUNOL.178.5.3143
Tengchuan Jin, Andrew Perry, Jiansheng Jiang, Patrick Smith, James A. Curry, Leonie Unterholzner, Zhaozhao Jiang, Gabor Horvath, Vijay A. Rathinam, Ricky W. Johnstone, Veit Hornung, Eicke Latz, Andrew G. Bowie, Katherine A. Fitzgerald, T. Sam Xiao, Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity. ,vol. 36, pp. 561- 571 ,(2012) , 10.1016/J.IMMUNI.2012.02.014
Hiroki Ishikawa, Zhe Ma, Glen N. Barber, STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity Nature. ,vol. 461, pp. 788- 792 ,(2009) , 10.1038/NATURE08476
Eicke Latz, The inflammasomes: mechanisms of activation and function. Current Opinion in Immunology. ,vol. 22, pp. 28- 33 ,(2010) , 10.1016/J.COI.2009.12.004
Ken J Ishii, Cevayir Coban, Hiroki Kato, Ken Takahashi, Yuichi Torii, Fumihiko Takeshita, Holger Ludwig, Gerd Sutter, Koichi Suzuki, Hiroaki Hemmi, Shintaro Sato, Masahiro Yamamoto, Satoshi Uematsu, Taro Kawai, Osamu Takeuchi, Shizuo Akira, A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nature Immunology. ,vol. 7, pp. 40- 48 ,(2006) , 10.1038/NI1282
Daxing Gao, Jiaxi Wu, You-Tong Wu, Fenghe Du, Chukwuemika Aroh, Nan Yan, Lijun Sun, Zhijian J. Chen, Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses Science. ,vol. 341, pp. 903- 906 ,(2013) , 10.1126/SCIENCE.1240933
Paolo S. Manzanillo, Michael U. Shiloh, Daniel A. Portnoy, Jeffery S. Cox, Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages Cell Host & Microbe. ,vol. 11, pp. 469- 480 ,(2012) , 10.1016/J.CHOM.2012.03.007
Christian Münz, Jan D. Lünemann, Meghann Teague Getts, Stephen D. Miller, Antiviral immune responses: triggers of or triggered by autoimmunity? Nature Reviews Immunology. ,vol. 9, pp. 246- 258 ,(2009) , 10.1038/NRI2527