Occurrence and risk assessment of fluoroquinolones and tetracyclines in cultured fish from a coastal region of northern China

摘要: Occurrence and levels of 11 fluoroquinolones (FQs) four tetracyclines (TC) in 14 cultured fish species from a coastal city the northern China were investigated. Five FQs (ofloxacin, enoxacin, ciprofloxacin, enrofloxacin, sarafloxacin) oxytetracycline detected. Lower detection frequencies antibiotics observed marine fish. The concentrations ΣFQs ranged not detectable (nd) to 130 ng/g wet weight (ww) (median, 7.2 ng/g ww), concentration range ΣTCs was nd 200 ng/g ww ng/g ww). Chinese snakehead contained highest (130 ng/g ww) small yellow croaker accumulated (200 ng/g respectively. Although calculated estimated daily intakes (EDI) suggested that consumption these this region associated with significant human health risks, study provides useful information will be helpful appropriate antibiotic use aquaculture. To our knowledge, can first report on occurrence cage-cultured Bohai Rim region, China.