Age and co-morbidity in cancer patients: a population-based approach.

作者: Maryska L. G. Janssen-Heijnen , Saskia Houterman , Valery E. P. P. Lemmens , Marieke W. J. Louwman , Jan Willem W. Coebergh

DOI: 10.1007/0-387-23962-6_5

关键词:

摘要: There is now clear evidence that the prevalence of co-morbidity among older cancer patients high and (with comorbidity) are often treated less aggressively, which seems to have a negative influence on survival. However, would outcomes really improve if more were treated, according guidelines developed basis results in groups younger without co-morbidity? Would complications occur with If case, it possible develop special treatment regimens for adapt guidelines? It remains relevant study age toxicity from treatment, quality life prognosis unselected patients.

参考文章(39)
Post, Kil, Hendrikx¶, Janssen-Heijnen, Crommelin, Coebergh, Comorbidity in patients with prostate cancer and its relevance to treatment choice. BJUI. ,vol. 84, pp. 652- 656 ,(2001) , 10.1046/J.1464-410X.1999.00279.X
Rosemary Yancik, Patricia A. Ganz, Claudette G. Varricchio, Barbara Conley, Perspectives on Comorbidity and Cancer in Older Patients: Approaches to Expand the Knowledge Base Journal of Clinical Oncology. ,vol. 19, pp. 1147- 1151 ,(2001) , 10.1200/JCO.2001.19.4.1147
P.N. Post, B.E. Hansen, P.J.M. Kil, M.L.G. Janssen-Heijnen, J.W.W. Coebergh, The independent prognostic value of comorbidity among men aged < 75 years with localized prostate cancer: a population-based study BJU International. ,vol. 87, pp. 821- 826 ,(2001) , 10.1046/J.1464-410X.2001.02189.X
Fabio Parazzini, Carlo La Vecchia, Luca Bocciolone, Silvia Franceschi, The epidemiology of endometrial cancer Gynecologic Oncology. ,vol. 41, pp. 1- 16 ,(1991) , 10.1016/0090-8258(91)90246-2
L B Koppert, M LG Janssen-Heijnen, M WJ Louwman, V EPP Lemmens, B PL Wijnhoven, H W Tilanus, J WW Coebergh, Comparison of comorbidity prevalence in oesophageal and gastric carcinoma patients European Journal of Gastroenterology & Hepatology. ,vol. 16, pp. 681- 688 ,(2004) , 10.1097/01.MEG.0000108331.52416.F1
Mary E. Charlson, Peter Pompei, Kathy L. Ales, C.Ronald MacKenzie, A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation☆ Journal of Chronic Diseases. ,vol. 40, pp. 373- 383 ,(1987) , 10.1016/0021-9681(87)90171-8
Jay F. Piccirillo, Importance of Comorbidity in Head and Neck Cancer Laryngoscope. ,vol. 110, pp. 593- 602 ,(2000) , 10.1097/00005537-200004000-00011
Brian N. Stein, Nicholas J. Petrelli, Harold O. Douglass, Deborah L. Driscoll, Giuseppina Arcangeli, Neal J. Meropol, Age and sex are independent predictors of 5-fluorouracil toxicity. Analysis of a large scale phase III trial Cancer. ,vol. 75, pp. 11- 17 ,(1995) , 10.1002/1097-0142(19950101)75:1<11::AID-CNCR2820750104>3.0.CO;2-N
Timo Hakulinen, Kamal H. Abeywickrama, A computer program package for relative survival analysis. Computer Programs in Biomedicine. ,vol. 19, pp. 197- 207 ,(1985) , 10.1016/0010-468X(85)90011-X
J.W.W Coebergh, M.L.G Janssen-Heijnen, P.N Post, P.P.A Razenberg, Serious Co-morbidity among unselected Cancer patients newly diagnosed in the southeastern part of the Netherlands in 1993-1996 Journal of Clinical Epidemiology. ,vol. 52, pp. 1131- 1136 ,(1999) , 10.1016/S0895-4356(99)00098-0