Pseudogene rescue: an adaptive mechanism of codon reassignment

摘要: Alterations to the genetic code – codon reassignments have occurred many times in life’s history, despite fact that genomes are coadapted their codes and therefore alterations likely be maladaptive. A potential mechanism for adaptive reassignment, which could trigger either a temporary period of ambiguity or permanent change, is reactivation pseudogene by nonsense suppressor mutant transfer RNA. I examine population genetics each stage this process find rescue plausible also readily explains some features extant variability codes.