Endocrine problems in the menopause.

摘要: The climacteric is an interval characterized by a multitude of physiologic, psychologic, and sociologic alterations that result in individual's adaptation to life beyond reproduction. common denominator the physiologic changes loss functional ovarian follicles their ability produce estradiol. relative estrogen deficiency results myriad systemic changes, some which themselves may impair quality or be life-threatening. Estrogen replacement therapy effective alleviating these including osteoporosis, vasomotor symptoms, genital atrophy. This treatment, however, confers additional risks, endometrial adenocarcinoma being one greatest concern. risk can reduced carefully selecting patients treated, closely following them, minimizing duration amount exposure, adding progestin regimen. It hoped cancer other adverse reactions associated with use further when more data regarding optimum dosage choice agents are available.