Purification and properties of a nerve growth-promoting factor isolated from mouse sarcoma 180.
作者： Rita Levi-Montalcini , Stanley Cohen
DOI:
关键词:
摘要: Summary A heat-labile, nondialyzable factor with nerve growth-promoting properties has been partially purified from Sarcoma 180. The data indicate that the active material is a protein or bound to and nucleic acids are not involved in its effectiveness. must be continuously present cultures for outgrowth of fibers proceed. was inhibited by iodoacetate, but cyanide, dinitrophenol, fluoride.
aacrjournals.org参考文章(6)
Walter C. Schneider, INTRACELLULAR DISTRIBUTION OF ENZYMES III. THE OXIDATION OF OCTANOIC ACID BY RAT LIVER FRACTIONS Journal of Biological Chemistry. ,vol. 176, pp. 259- 266 ,(1948) , 10.1016/S0021-9258(18)51025-5
NELSON T. SPRATT, NUTRITIONAL REQUIREMENTS OF THE EARLY CHICK EMBRYO. III. THE METABOLIC BASIS OF MORPHOGENESIS AND DIFFERENTIATION AS REVEALED BY THE USE OF INHIBITORS The Biological Bulletin. ,vol. 99, pp. 120- 135 ,(1950) , 10.2307/1538756
Rita Levi-Montalcini, Viktor Hamburger, Hertha Meyer, In vitro experiments on the effects of mouse sarcomas 180 and 37 on the spinal and sympathetic ganglia of the chick embryo. Cancer Research. ,vol. 14, pp. 49- 57 ,(1954)
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
Elmer D. Bueker, Implantation of tumors in the hind limb field of the embryonic chick and the developmental response of the lumbosacral nervous system The Anatomical Record. ,vol. 102, pp. 369- 389 ,(1948) , 10.1002/AR.1091020309
Rita Levi-Montalcini, Viktor Hamburger, A diffusible agent of mouse sarcoma, producing hyperplasia of sympathetic ganglia and hyperneurotization of viscera in the chick embryo Journal of Experimental Zoology. ,vol. 123, pp. 233- 287 ,(1953) , 10.1002/JEZ.1401230203