Computer-generated pictures of proteins

作者: Arthur M. Lesk , Karl D. Hardman

DOI: 10.1016/0076-6879(85)15027-5

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摘要: Publisher Summary This chapter describes the applications of a computer program that draws stereoscopic pictures biological macromolecules. The makes it easy to explore various ways depicting structure, including free mixing in single drawing different styles representation portions molecule, together with labels and comments. initial motives for applying graphics are unwieldliness instability physical models their readiness denature, fact space material requirements increase as more structures appear. To gain ability produce diagrams provide flexibility essential mix representations one picture, has been compiled into coherent many macromolecules have proved utility. visual display is principal tool computational molecular biology. discusses basic operation program. It includes line drawings, picture generation color-raster output.

参考文章(10)
D.A. Matthews, R.A. Alden, J.T. Bolin, D.J. Filman, S.T. Freer, R. Hamlin, W.G. Hol, R.L. Kisliuk, E.J. Pastore, L.T. Plante, N. Xuong, J. Kraut, Dihydrofolate reductase from Lactobacillus casei. X-ray structure of the enzyme methotrexate.NADPH complex. Journal of Biological Chemistry. ,vol. 253, pp. 6946- 6954 ,(1978) , 10.1016/S0021-9258(17)38012-2
K.D. Hardman, C.F. Ainsworth, Structure of concanavalin A at 2.4-A resolution. Biochemistry. ,vol. 11, pp. 4910- 4919 ,(1972) , 10.2210/PDB3CNA/PDB
Phosphofructokinase: structure and control. Philosophical Transactions of the Royal Society B. ,vol. 293, pp. 53- 62 ,(1989) , 10.1098/RSTB.1981.0059
E.N. Baker, Structure of actinidin, after refinement at 1.7 Å resolution Journal of Molecular Biology. ,vol. 141, pp. 441- 484 ,(1980) , 10.1016/0022-2836(80)90255-7
J. Deisenhofer, W. Steigemann, Crystallographic refinement of the structure of bovine pancreatic trypsin inhibitor at l.5 Å resolution Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. ,vol. 31, pp. 238- 250 ,(1975) , 10.1107/S0567740875002415
A. Lesk, K. Hardman, Computer-generated schematic diagrams of protein structures Science. ,vol. 216, pp. 539- 540 ,(1982) , 10.1126/SCIENCE.7071602
P. M. Colman, H. C. Freeman, J. M. Guss, M. Murata, V. A. Norris, J. A. M. Ramshaw, M. P. Venkatappa, X-ray crystal structure analysis of plastocyanin at 2.7 Å resolution Nature. ,vol. 272, pp. 319- 324 ,(1978) , 10.1038/272319A0
Ernst Weber, Wolfgang Steigemann, T.Alwyn Jones, Robert Huber, The structure of oxy-erythrocruorin at 1.4 Å resolution Journal of Molecular Biology. ,vol. 120, pp. 327- 336 ,(1978) , 10.1016/0022-2836(78)90071-2
Karl D. Hardman, Clinton F. Ainsworth, Structure of concanavalin A at 2.4-Ang resolution Biochemistry. ,vol. 11, pp. 4910- 4919 ,(1972) , 10.1021/BI00776A006