Transcutaneous Spinal Direct Current Stimulation Alters Resting-State Functional Connectivity.

作者: Lauren Schweizer , Christine H. Meyer-Frießem , Peter K. Zahn , Martin Tegenthoff , Tobias Schmidt-Wilcke

DOI: 10.1089/BRAIN.2017.0505

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摘要: Abstract Transcutaneous spinal direct current stimulation (tsDCS) is a noninvasive method that can modulate reflexes, sensory afferent conduction, and even pain perception. Although neurophysiological evidence suggests tsDCS alters somatosensory nociceptive conduction to the cortex, its supraspinal effects have not yet been investigated by using functional imaging investigate tsDCS-induced alterations in intrinsic connectivity (FC). Therefore, we hypothesize changes measures might also be reflected spontaneous brain activity. We cortical seed-to-voxel-based analyses from bilateral primary cortex (S1) thalamus double-blind, crossover study design. Resting state FC was measured blood oxygenation level-dependent, magnetic resonance (3T Philips) before after anodal, cathodal, sham (2...

参考文章(52)
Tommaso Bocci, Matteo Caleo, Beatrice Vannini, Maurizio Vergari, Filippo Cogiamanian, Simone Rossi, Alberto Priori, Ferdinando Sartucci, An unexpected target of spinal direct current stimulation: Interhemispheric connectivity in humans. Journal of Neuroscience Methods. ,vol. 254, pp. 18- 26 ,(2015) , 10.1016/J.JNEUMETH.2015.07.012
J. Aguilar, F. Pulecchi, R. Dilena, A. Oliviero, A. Priori, G. Foffani, Spinal direct current stimulation modulates the activity of gracile nucleus and primary somatosensory cortex in anaesthetized rats. The Journal of Physiology. ,vol. 589, pp. 4981- 4996 ,(2011) , 10.1113/JPHYSIOL.2011.214189
G. Batsikadze, V. Moliadze, W. Paulus, M.-F. Kuo, M. A. Nitsche, Partially non-linear stimulation intensity-dependent effects of direct current stimulation on motor cortex excitability in humans The Journal of Physiology. ,vol. 591, pp. 1987- 2000 ,(2013) , 10.1113/JPHYSIOL.2012.249730
M. D. Fox, A. Z. Snyder, J. L. Vincent, M. Corbetta, D. C. Van Essen, M. E. Raichle, The human brain is intrinsically organized into dynamic, anticorrelated functional networks Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 9673- 9678 ,(2005) , 10.1073/PNAS.0504136102
Lauren Haag, Clara Quetscher, Shalmali Dharmadhikari, Ulrike Dydak, Tobias Schmidt-Wilcke, Christian Beste, Interrelation of resting state functional connectivity, striatal GABA levels, and cognitive control processes Human Brain Mapping. ,vol. 36, pp. 4383- 4393 ,(2015) , 10.1002/HBM.22920
Simon M. Danner, Ursula S. Hofstoetter, Josef Ladenbauer, Frank Rattay, Karen Minassian, Can the Human Lumbar Posterior Columns Be Stimulated by Transcutaneous Spinal Cord Stimulation? A Modeling Study Artificial Organs. ,vol. 35, pp. 257- 262 ,(2011) , 10.1111/J.1525-1594.2011.01213.X
A. Truini, M. Vergari, A. Biasiotta, S. La Cesa, M. Gabriele, G. Di Stefano, C. Cambieri, G. Cruccu, M. Inghilleri, A. Priori, Transcutaneous spinal direct current stimulation inhibits nociceptive spinal pathway conduction and increases pain tolerance in humans. European Journal of Pain. ,vol. 15, pp. 1023- 1027 ,(2011) , 10.1016/J.EJPAIN.2011.04.009
Anthony B. Waites, Alexandra Stanislavsky, David F. Abbott, Graeme D. Jackson, Effect of prior cognitive state on resting state networks measured with functional connectivity. Human Brain Mapping. ,vol. 24, pp. 59- 68 ,(2005) , 10.1002/HBM.20069
Peter K. Toshev, Berkan Guleyupoglu, Marom Bikson, Informing dose design by modeling transcutaneous spinal direct current stimulation. Clinical Neurophysiology. ,vol. 125, pp. 2147- 2149 ,(2014) , 10.1016/J.CLINPH.2014.03.022
C.H. Meyer-Frießem, L.M. Haag, T. Schmidt-Wilcke, W. Magerl, E.M. Pogatzki-Zahn, M. Tegenthoff, P.K. Zahn, Transcutaneous spinal DC stimulation reduces pain sensitivity in humans Neuroscience Letters. ,vol. 589, pp. 153- 158 ,(2015) , 10.1016/J.NEULET.2015.01.029