The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells
作者： Richard A. Oram , Angus G. Jones , Rachel E. J. Besser , Bridget A. Knight , Beverley M. Shields
DOI: 10.1007/S00125-013-3067-X
关键词:
摘要: Aims/hypothesis Classically, type 1 diabetes is thought to proceed absolute insulin deficiency. Recently developed ultrasensitive assays capable of detecting C-peptide under 5 pmol/l now allow very low levels be detected in patients with long-standing diabetes. It not known whether this low-level endogenous secretion responds physiological stimuli. We aimed assess how commonly detectable occurs long-duration and it a meal stimulus.
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